Choosing Wisely Manitoba (CWMB) was formalized in 2014 and is led in partnership by Shared Health and the George and Fay Yee Centre for Healthcare Innovation. CWMB is an initiative to improve health outcomes, patient and provider experiences and create health system efficiencies and sustainability through its partnership with Choosing Wisely Canada. Initial efforts have focused on the information and processes needed to challenge test practices and to move toward a model where tests are more appropriately ordered. This has included extensive engagement and collaboration with clinicians and key stakeholders such as the College of Physicians and Surgeons of Manitoba, Doctors Manitoba, Manitoba Centre for Health Policy, the University of Manitoba Faculty of Health Sciences, the College of Pharmacists of Manitoba and the provincial regional health authorities.